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KMID : 1094720080130020252
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Biotechnology and Bioprocess Engineering
2008 Volume.13 No. 2 p.252 ~ p.255
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The effect of cetylpyridinium chloride on halitosis and periodontal disease-related parameters in dogs
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Kim Se-Eun
Shim Kyung-Mi
Yoo Kyeong-Hoon
Kim Jong-Choon
Kim Seong-Ho
Bae Chun-Sik
Kim Do-Man
Park Don-Hee
Ryu Ji-Won
Kang Seong-Soo
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Abstract
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Periodontal disease is an oral disease common in middle-aged dogs and cats, with halitosis being the most common sign. There are many commercial products containing chlorhexidine, cetylpyridinium chloride (CPC), zinc salts and essential oils for controlling halitosis and periodontal disease. CPC is a quaternary ammonium compound and has a broad spectrum antimicrobial activity. In this study, oral spray (OS) and gel (OG) containing CPC was applied to the dogs’ teeth twice daily for 3 weeks, and their effect in controlling periodontal disease and halitosis was examined. In the 3-week study, OS and OG were significantly effective in controlling plaque, calculus, and halitosis. Therefore, the OS and OG containing CPC were effective in controlling periodontal disease and halitosis in dogs.
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KEYWORD
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cetylpyridinium chloride, halitosis, periodontal disease, dog
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